English Name: Bottle Gourd
Arabic Name: Garra
Urdu Name: Looki | Distribution: Africa, Asia, Europe, America
Parts used: Fruit, Seed
Medicinal Uses | Lagenaria siceraria (Molina) Standley (family Cucurbitaceae), commonly known as lauki (Hindi) and bottle gourd (English), is a medicinal plant and utilizable species. Lagenaria siceraria fruit is traditionally used for its cardioprotective, cardiotonic, general tonic, and aphrodisiac properties. It is also used in the treatment of various allergic and inflammatory disorders like bronchial asthma, rhinitis, bronchitis, and rheumatism. Various extracts of fruits of Lagenaria siceraria were found to have anti-inflammatory, analgesic, hepatoprotective, antihyperlipidemic, diuretic, and antibacterial activities. Methanol extract of fruits was found to contain flavonoids, saponins, tannins, carbohydrates, and terpenoids. A novel ribosome-inactivating protein, lignin has been isolated from seeds of Lagenaria siceraria. Fruits are reported to contain more soluble dietary fibers than insoluble cellulose fibers. The fruits are considered a good source of vitamin C, β-carotene, vitamin B-complex, pectin and also contain the highest choline level- a lipoprotein factor. Few of these primary and secondary metabolites have been implicated in the reported uses of Lagenaria siceraria fruits. Previously we have reported the immunomodulatory activity of ethyl acetate and n butanol soluble parts of the successive methanol extract of Lagenaria siceraria fruits and immunomodulatory activity of purified saponin mixture extracted from the fruit of Lagenaria siceraria.